Epistatic interaction between PKD2 and ABCG2 influences the pathogenesis of hyperuricemia and gout

BACKGROUND: Genetic background affects serum urate concentration and gout risk, especially regarding these variants in the urate-transporter gene ABCG2. However, the role of epistasis between PKD2 and ABCG2 on the pathogenesis of gout is poorly understood. Here we assess this epistatic interaction i...

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Detalles Bibliográficos
Autores principales: Dong, Zheng, Zhou, Jingru, Jiang, Shuai, Li, Yuan, Zhao, Dongbao, Yang, Chengde, Ma, Yanyun, He, Hongjun, Ji, Hengdong, Jin, Li, Zou, Hejian, Wang, Jiucun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986014/
https://www.ncbi.nlm.nih.gov/pubmed/32000861
http://dx.doi.org/10.1186/s41065-020-0116-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986014/
https://www.ncbi.nlm.nih.gov/pubmed/32000861
http://dx.doi.org/10.1186/s41065-020-0116-6

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