Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components

BACKGROUND: Cell death triggered by unmitigated endoplasmic reticulum (ER) stress plays an important role in physiology and disease, but the death-inducing signaling mechanisms are incompletely understood. To gain more insight into these mechanisms, the ER stressor thapsigargin (Tg) is an instrument...

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Detalles Bibliográficos
Autores principales: Lindner, Paula, Christensen, Søren Brøgger, Nissen, Poul, Møller, Jesper Vuust, Engedal, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986015/
https://www.ncbi.nlm.nih.gov/pubmed/31987044
http://dx.doi.org/10.1186/s12964-019-0499-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986015/
https://www.ncbi.nlm.nih.gov/pubmed/31987044
http://dx.doi.org/10.1186/s12964-019-0499-z

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