The role of the redox/miR-6855-3p/PRDX5A axis in reversing SLUG-mediated BRCA2 silencing in breast cancer cells

BACKGROUND: We have previously shown that the zinc finger transcription repressor SNAI2 (SLUG) represses tumor suppressor BRCA2-expression in non-dividing cells by binding to the E2-box upstream of the transcription start site. However, it is unclear how proliferating breast cancer (BC) cells that h...

Descripción completa

Detalles Bibliográficos
Autores principales: Ellison, Marshall, Mittal, Mukul, Chaudhuri, Minu, Chaudhuri, Gautam, Misra, Smita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986021/
https://www.ncbi.nlm.nih.gov/pubmed/31987042
http://dx.doi.org/10.1186/s12964-019-0493-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986021/
https://www.ncbi.nlm.nih.gov/pubmed/31987042
http://dx.doi.org/10.1186/s12964-019-0493-5

Ejemplares similares