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Demonstration of anti-tumour bystander killing with prodrug-preloaded suicide gene-engineered tumour cells: a potential improvement for cancer therapeutics

BACKGROUND: Therapeutic approaches for cancer rely on careful consideration of finding the optimal way of delivering the pro-drug for cellular-based cancer treatment. Cell lines and cell cultures have been used in these studies to compare the in vitro and in vivo efficacy of autologous vs. allogenei...

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Detalles Bibliográficos
Autores principales: Zweiri, Jehad, Christmas, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986055/
https://www.ncbi.nlm.nih.gov/pubmed/32002015
http://dx.doi.org/10.1186/s12935-020-1115-4