Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function

BACKGROUND: Nebulin is a critical thin filament-binding protein that spans from the Z-disk of the skeletal muscle sarcomere to near the pointed end of the thin filament. Its massive size and actin-binding property allows it to provide the thin filaments with structural and regulatory support. When t...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Frank, Kolb, Justin, Crudele, Julie, Hourani, Zaynab, Smith, John E., Chamberlain, Jeffrey S., Granzier, Henk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986074/
https://www.ncbi.nlm.nih.gov/pubmed/31992366
http://dx.doi.org/10.1186/s13395-019-0219-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986074/
https://www.ncbi.nlm.nih.gov/pubmed/31992366
http://dx.doi.org/10.1186/s13395-019-0219-9

Ejemplares similares