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QuantTB – a method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data

BACKGROUND: Mixed infections of Mycobacterium tuberculosis and antibiotic heteroresistance continue to complicate tuberculosis (TB) diagnosis and treatment. Detection of mixed infections has been limited to molecular genotyping techniques, which lack the sensitivity and resolution to accurately esti...

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Detalles Bibliográficos
Autores principales: Anyansi, Christine, Keo, Arlin, Walker, Bruce J., Straub, Timothy J., Manson, Abigail L., Earl, Ashlee M., Abeel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986090/
https://www.ncbi.nlm.nih.gov/pubmed/31992201
http://dx.doi.org/10.1186/s12864-020-6486-3