A comparison of curated gene sets versus transcriptomics-derived gene signatures for detecting pathway activation in immune cells

BACKGROUND: Despite the significant contribution of transcriptomics to the fields of biological and biomedical research, interpreting long lists of significantly differentially expressed genes remains a challenging step in the analysis process. Gene set enrichment analysis is a standard approach for...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Lindner, Patrick, Jirmo, Adan Chari, Maus, Ulrich, Illig, Thomas, DeLuca, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986093/
https://www.ncbi.nlm.nih.gov/pubmed/31992182
http://dx.doi.org/10.1186/s12859-020-3366-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986093/
https://www.ncbi.nlm.nih.gov/pubmed/31992182
http://dx.doi.org/10.1186/s12859-020-3366-4

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