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Uncovering New Mutations Conferring Azole Resistance in the Aspergillus fumigatus cyp51A Gene
The opportunistic pathogen Aspergillus fumigatus has developed worldwide resistance to azoles largely through mutations in cytochromeP450 enzyme Cyp51. In this study, we indicated that in vitro azole situation results in emergence of azole-resistant mutations. There are previously identified azole-r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986205/ https://www.ncbi.nlm.nih.gov/pubmed/32038564 http://dx.doi.org/10.3389/fmicb.2019.03127 |