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Uncovering New Mutations Conferring Azole Resistance in the Aspergillus fumigatus cyp51A Gene

The opportunistic pathogen Aspergillus fumigatus has developed worldwide resistance to azoles largely through mutations in cytochromeP450 enzyme Cyp51. In this study, we indicated that in vitro azole situation results in emergence of azole-resistant mutations. There are previously identified azole-r...

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Detalles Bibliográficos
Autores principales: Chen, Peiying, Liu, Musang, Zeng, Qiuqiong, Zhang, Zheng, Liu, Weida, Sang, Hong, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986205/
https://www.ncbi.nlm.nih.gov/pubmed/32038564
http://dx.doi.org/10.3389/fmicb.2019.03127