Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene

BACKGROUND: Romidepsin (FK228) or depsipeptide, is a selective inhibitor of histone deacetylase 1 (HDAC1) and HDAC2. This study aimed to investigate the effects and molecular mechanisms of romidepsin (FK228) in a mouse model of acute kidney injury (AKI) induced by lipopolysaccharide (LPS). MATERIAL/...

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Detalles Bibliográficos
Autores principales: Cheng, Shulin, Wu, Tao, Li, Yugen, Huang, Jing, Cai, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986234/
https://www.ncbi.nlm.nih.gov/pubmed/31954012
http://dx.doi.org/10.12659/MSM.918528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986234/
https://www.ncbi.nlm.nih.gov/pubmed/31954012
http://dx.doi.org/10.12659/MSM.918528

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