Cargando…

Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene

BACKGROUND: Romidepsin (FK228) or depsipeptide, is a selective inhibitor of histone deacetylase 1 (HDAC1) and HDAC2. This study aimed to investigate the effects and molecular mechanisms of romidepsin (FK228) in a mouse model of acute kidney injury (AKI) induced by lipopolysaccharide (LPS). MATERIAL/...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Shulin, Wu, Tao, Li, Yugen, Huang, Jing, Cai, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2020
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986234/ https://www.ncbi.nlm.nih.gov/pubmed/31954012 http://dx.doi.org/10.12659/MSM.918528

Ejemplares similares

Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors
por: Saijo, Ken, et al.
Publicado: (2015)

Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer
por: Shi, Yehui, et al.
Publicado: (2020)

FK228 from Burkholderia thailandensis MSMB43
por: Liu, Xiang-Yang, et al.
Publicado: (2012)

Protective Effect of Dihydromyricetin Against Lipopolysaccharide-Induced Acute Kidney Injury in a Rat Model
por: Wang, Jun-Tao, et al.
Publicado: (2016)

Astragaloside IV Alleviates Lipopolysaccharide-Induced Acute Kidney Injury Through Down-Regulating Cytokines, CCR5 and p-ERK, and Elevating Anti-Oxidative Ability
por: Zhou, Wei, et al.
Publicado: (2017)

FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors
por: Makala, Levi, et al.
Publicado: (2012)

The structural basis of an NADP(+)-independent dithiol oxidase in FK228 biosynthesis
por: Li, Jie, et al.
Publicado: (2014)

FK228 sensitizes radioresistant small cell lung cancer cells to radiation
por: Li, Hong, et al.
Publicado: (2021)

Mechanistic studies of DepR in regulating FK228 biosynthesis in Chromobacterium violaceum no. 968
por: Qiao, Yongjian, et al.
Publicado: (2018)

Apoptotic Cytotoxic Effects of a Histone Deacetylase Inhibitor, FK228, on Malignant Lymphoid Cells
por: Murata, Makoto, et al.
Publicado: (2000)

Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228
por: Liu, Xiangyang, et al.
Publicado: (2018)

Protective Effects of Luteolin on Lipopolysaccharide-Induced Acute Renal Injury in Mice
por: Xin, Shao-bin, et al.
Publicado: (2016)

Ouabain Protects Mice Against Lipopolysaccharide-Induced Acute Lung Injury
por: Wang, Changli, et al.
Publicado: (2018)

Pantethine Down-Regulates Leukocyte Recruitment and Inflammatory Parameters in a Mouse Model of Allergic Airway Inflammation
por: Abou-Hamdan, Mhamad, et al.
Publicado: (2017)

Down-Regulation of Fibroblast Growth Factor 2 (FGF2) Contributes to the Premature Senescence of Mouse Embryonic Fibroblast
por: Li, Jie, et al.
Publicado: (2020)

Effect of Slug-Mediated Down-Regulation of E-Cadherin on Invasiveness and Metastasis of Anaplastic Thyroid Cancer Cells
por: Sheng, Li, et al.
Publicado: (2017)

Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Cyclosporine-A via Suppression of Mitochondrial DNA
por: Xiao, Zhenghua, et al.
Publicado: (2018)

Lipopolysaccharide-Induced Acute Lung Injury Is Associated with Increased Ran-Binding Protein in Microtubule-Organizing Center (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis Signaling Pathway in a Mouse Model
por: Lv, Xiaojing, et al.
Publicado: (2020)

The Effects of Dimethyl Fumarate on Atherosclerosis in the Apolipoprotein E-Deficient Mouse Model with Streptozotocin-Induced Hyperglycemia Mediated By the Nuclear Factor Erythroid 2-Related Factor 2/Antioxidant Response Element (Nrf2/ARE) Signaling Pathway
por: Luo, Man, et al.
Publicado: (2019)

Carbon Monoxide Attenuates Lipopolysaccharides (LPS)-Induced Acute Lung Injury in Neonatal Rats via Downregulation of Cx43 to Reduce Necroptosis
por: Li, Wanwei, et al.
Publicado: (2019)

The HDAC Inhibitor FK228 Enhances Adenoviral Transgene Expression by a Transduction-Independent Mechanism but Does Not Increase Adenovirus Replication
por: Danielsson, Angelika, et al.
Publicado: (2011)

Evaluation of CYP3A‐mediated drug–drug interactions with romidepsin in patients with advanced cancer
por: Laille, Eric, et al.
Publicado: (2015)

Smoking Attenuates Efficacy of Penehyclidine Hydrochloride in Acute Respiratory Distress Syndrome Induced by Lipopolysaccharide in Rats
por: Zhao, Hongyan, et al.
Publicado: (2019)

Protective Effects of MiR-129-5p on Acute Spinal Cord Injury Rats
por: Yang, Ruifeng, et al.
Publicado: (2019)

Treating Colon Cancer Cells with FK228 Reveals a Link between Histone Lysine Acetylation and Extensive Changes in the Cellular Proteome
por: Wang, Tian-yun, et al.
Publicado: (2015)

In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi‐scid/scid Mice
por: Kosugi, Hiroshi, et al.
Publicado: (2001)

Combinatorial Antitumor Activity of Oxaliplatin with Epigenetic Modifying Agents, 5-Aza-CdR and FK228, in Human Gastric Cancer Cells
por: Park, Jong Kook, et al.
Publicado: (2018)

Lipopolysaccharide Exposure Alleviates Asthma in Mice by Regulating Th1/Th2 and Treg/Th17 Balance
por: Ding, Fengxia, et al.
Publicado: (2018)

Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis
por: Dong, Wen-Wen, et al.
Publicado: (2017)

MicroRNA-506 Is Involved in Regulation of the Occurrence of Lipopolysaccharides (LPS)-Induced Pulpitis by Sirtuin 1 (SIRT1)
por: Wang, Jun, et al.
Publicado: (2019)

Romidepsin-induced neutrophilic urticaria
por: Scott, Brian, et al.
Publicado: (2016)

Metastasis-Associated 1 (MTA1) Gene Expression Promotes Angiogenesis in Mouse Xenografts from Human Non-Small Cell Lung Cancer (NSCLC) Cells
por: Wang, Tao, et al.
Publicado: (2019)

Effects of Zinc Finger Protein A20 on Lipopolysaccharide (LPS)-Induced Pulmonary Inflammation/Anti-Inflammatory Mediators in an Acute Lung Injury/Acute Respiratory Distress Syndrome Rat Model
por: Wu, Ding-Qian, et al.
Publicado: (2017)

Long Noncoding RNA FTX Reduces Hypertrophy of Neonatal Mouse Cardiac Myocytes and Regulates the PTEN/PI3K/Akt Signaling Pathway by Sponging MicroRNA-22
por: Yang, Xiaoyu, et al.
Publicado: (2019)

Tetrahydropyrimidines, ZL-5015 Alleviated Lipopolysaccharide (LPS)-Induced Acute Pneumonia in Rats by Activating the NRF-2/HO-1 Pathway
por: Sun, Wei, et al.
Publicado: (2020)

Puerarin Inhibits Endothelium-Dependent Contractions in Mouse Carotid Arteries
por: Chen, Mei, et al.
Publicado: (2020)

Relationship Between INPP5E Gene Expression and Embryonic Neural Development in a Mouse Model of Neural Tube Defect
por: Yue, Huixuan, et al.
Publicado: (2018)

Heliox-Driven Nebulization Has a Positive Effect on the Lung Function in Lipopolysaccharide-Induced Chronic Obstructive Pulmonary Disease Rat Model
por: Wu, Wenwen, et al.
Publicado: (2016)

Interleukin-37 Attenuates Lipopolysaccharide (LPS)-Induced Neonatal Acute Respiratory Distress Syndrome in Young Mice via Inhibition of Inflammation and Cell Apoptosis
por: Li, Bo, et al.
Publicado: (2020)

Intermedin 1-53 Inhibits Myocardial Fibrosis in Rats by Down-Regulating Transforming Growth Factor-β
por: Fang, Jian, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_so5d4c5co7u7seiq1qf01vcn02