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Identification of Small-Molecule Inhibitors of Brucella Diaminopimelate Decarboxylase by Using a High-Throughput Screening Assay

Brucellosis, caused by intracellular gram-negative pathogens of the genus Brucella, continues to be one of the most pandemic zoonotic diseases in most countries. At present, the therapeutic treatment of brucellosis relies on a combination of multiple antibiotics that involves a long course of treatm...

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Detalles Bibliográficos
Autores principales: Bie, Pengfei, Yang, Xiaowen, Zhang, Cunrui, Wu, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986272/
https://www.ncbi.nlm.nih.gov/pubmed/32038511
http://dx.doi.org/10.3389/fmicb.2019.02936