Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China

OBJECTIVE: Pyrazinamide (PZA) is a cornerstone of modern tuberculosis regimens. This study aimed to investigate the performance of genotypic testing of pncA(+) upstream region, rpsA, panD, Rv2783c, and clpC1 genes to add insights for more accurate molecular diagnosis of PZA-resistant (R) Mycobacteri...

Descripción completa

Detalles Bibliográficos
Autores principales: Hameed, HM Adnan, Tan, Yaoju, Islam, Md Mahmudul, Lu, Zhili, Chhotaray, Chiranjibi, Wang, Shuai, Liu, Zhiyong, Fang, Cuiting, Tan, Shouyong, Yew, Wing Wai, Zhong, Nanshan, Liu, Jianxiong, Zhang, Tianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986415/
https://www.ncbi.nlm.nih.gov/pubmed/32158237
http://dx.doi.org/10.2147/IDR.S230774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986415/
https://www.ncbi.nlm.nih.gov/pubmed/32158237
http://dx.doi.org/10.2147/IDR.S230774

Ejemplares similares