Interactions between TGF-β type I receptor and hypoxia-inducible factor-α mediates a synergistic crosstalk leading to poor prognosis for patients with clear cell renal cell carcinoma

To investigate the significance of expression of HIF-1α, HIF-2α, and SNAIL1 proteins; and TGF-β signaling pathway proteins in ccRCC, their relation with clinicopathological parameters and patient’s survival were examined. We also investigated potential crosstalk between HIF-α and TGF-β signaling pat...

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Detalles Bibliográficos
Autores principales: Mallikarjuna, Pramod, Raviprakash, Tumkur Sitaram, Aripaka, Karthik, Ljungberg, Börje, Landström, Marene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986558/
https://www.ncbi.nlm.nih.gov/pubmed/31339433
http://dx.doi.org/10.1080/15384101.2019.1642069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986558/
https://www.ncbi.nlm.nih.gov/pubmed/31339433
http://dx.doi.org/10.1080/15384101.2019.1642069

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