Self-Assembled Nanoparticles Prepared from Low-Molecular-Weight PEI and Low-Generation PAMAM for EGFRvIII-Chimeric Antigen Receptor Gene Loading and T-Cell Transient Modification

BACKGROUND: The complex preparation procedures and severe toxicities are two major obstacles facing the wide use of chimeric antigen receptor-modified T (CAR-T) cells in clinical cancer immunotherapy. The nanotechnology-based T cell temporary CAR modification may be a potential approach to solve the...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Qianru, Zhang, Maxin, Chen, Yuetan, Chen, Xiaolong, Shi, Sanyuan, Sun, Kang, Ye, Ran, Zheng, Yuan, Chen, Yang, Xu, Yuhong, Peng, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986680/
https://www.ncbi.nlm.nih.gov/pubmed/32158206
http://dx.doi.org/10.2147/IJN.S229858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986680/
https://www.ncbi.nlm.nih.gov/pubmed/32158206
http://dx.doi.org/10.2147/IJN.S229858

Ejemplares similares