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RNA binding protein FXR1-miR301a-3p axis contributes to p21(WAF1) degradation in oral cancer

RNA-binding proteins (RBPs) associate with the primary, precursor, and mature microRNAs, which in turn control post-transcriptional gene regulation. Here, by small RNAseq, we show that RBP FXR1 controls the expression of a subset of mature miRNAs, including highly expressed miR301a-3p in oral cancer...

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Detalles Bibliográficos
Autores principales: Majumder, Mrinmoyee, Palanisamy, Viswanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986764/
https://www.ncbi.nlm.nih.gov/pubmed/31940341
http://dx.doi.org/10.1371/journal.pgen.1008580