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Effects of Mlx-8, a phospholipase A(2) from Brazilian coralsnake Micrurus lemniscatus venom, on muscarinic acetylcholine receptors in rat hippocampus

BACKGROUND: Here, we described the presence of a neurotoxin with phospholipase A(2) activity isolated from Micrurus lemniscatus venom (Mlx-8) with affinity for muscarinic acetylcholine receptors (mAChRs). METHODS: The purification, molecular mass determination, partial amino acid sequencing, phospho...

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Detalles Bibliográficos
Autores principales: dos Santos, Roberta Tancredi Francesco, Silva, Marcelo Florencio Passos, Porto, Rafael Marques, Lebrun, Ivo, Gonçalves, Luís Roberto de Camargo, Batista, Isabel de Fátima Correia, Sandoval, Maria Regina Lopes, Abdalla, Fernando Maurício Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986814/
https://www.ncbi.nlm.nih.gov/pubmed/32063920
http://dx.doi.org/10.1590/1678-9199-JVATITD-2019-0041