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Multiplex CRISPR/Cas screen in regenerating haploid limbs of chimeric Axolotls

Axolotls and other salamanders can regenerate entire limbs after amputation as adults, and much recent effort has sought to identify the molecular programs controlling this process. While targeted mutagenesis approaches like CRISPR/Cas9 now permit gene-level investigation of these mechanisms, geneti...

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Detalles Bibliográficos
Autores principales: Sanor, Lucas D, Flowers, Grant Parker, Crews, Craig M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986871/
https://www.ncbi.nlm.nih.gov/pubmed/31989926
http://dx.doi.org/10.7554/eLife.48511