TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres

Telomeres are a significant challenge to DNA replication and are prone to replication stress and telomere fragility. The shelterin component TRF1 facilitates telomere replication but the molecular mechanism remains uncertain. By interrogating the proteomic composition of telomeres, we show that mous...

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Detalles Bibliográficos
Autores principales: Porreca, Rosa Maria, Herrera-Moyano, Emilia, Skourti, Eleni, Law, Pui Pik, Gonzalez Franco, Roser, Montoya, Alex, Faull, Peter, Kramer, Holger, Vannier, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986873/
https://www.ncbi.nlm.nih.gov/pubmed/31934863
http://dx.doi.org/10.7554/eLife.49817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986873/
https://www.ncbi.nlm.nih.gov/pubmed/31934863
http://dx.doi.org/10.7554/eLife.49817

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