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Preclinical murine tumor models: A structural and functional perspective

The goal of this review is to pinpoint the specific features, including the weaknesses, of various tumor models, and to discuss the reasons why treatments that are efficient in murine tumor models often do not work in clinics. In a detailed comparison of transplanted and spontaneous tumor models, we...

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Detalles Bibliográficos
Autores principales: Guerin, Marion V, Finisguerra, Veronica, Van den Eynde, Benoit J, Bercovici, Nadege, Trautmann, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986875/
https://www.ncbi.nlm.nih.gov/pubmed/31990272
http://dx.doi.org/10.7554/eLife.50740