Somatostatin secretion by Na(+)-dependent Ca(2+)-induced Ca(2+) release in pancreatic delta-cells

Pancreatic islets are complex micro-organs consisting of at least three different cell types: glucagon-secreting α-, insulin-producing β- and somatostatin-releasing δ-cells(1). Somatostatin is a powerful paracrine inhibitor of insulin and glucagon secretion(2). In diabetes, increased somatostatinerg...

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Detalles Bibliográficos
Autores principales: Vergari, Elisa, Denwood, Geoffrey, Salehi, Albert, Zhang, Quan, Adam, Julie, Alrifaiy, Ahmed, Wernstedt Asterholm, Ingrid, Benrick, Anna, Chibalina, Margarita V., Eliasson, Lena, Guida, Claudia, Hill, Thomas G., Hamilton, Alexander, Ramracheya, Reshma, Reimann, Frank, Rorsman, Nils J. G., Spilliotis, Ioannis, Tarasov, Andrei I., Walker, Jonathan N., Rorsman, Patrik, Briant, Linford J. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986923/
https://www.ncbi.nlm.nih.gov/pubmed/31993555
http://dx.doi.org/10.1038/s42255-019-0158-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986923/
https://www.ncbi.nlm.nih.gov/pubmed/31993555
http://dx.doi.org/10.1038/s42255-019-0158-0

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