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Butyric Acid Increases the Therapeutic Effect of EHLJ7 on Ulcerative Colitis by Inhibiting JAK2/STAT3/SOCS1 Signaling Pathway

Ulcerative colitis (UC) is a refractory chronic disease characterized by bloody diarrhea and mucosal or submucosal ulcers. There is an urgent need of new drugs for the treatment of ulcerative colitis. EHLJ7 is a quaternary coptisine derivative. Herein, we explored the therapeutic effect of EHLJ7 on...

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Detalles Bibliográficos
Autores principales: Tang, Xiaonan, Li, Xiang, Wang, Yufei, Zhang, ZhiHui, Deng, AnJun, Wang, WenJie, Zhang, Haijing, Qin, Hailin, Wu, LianQiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987075/
https://www.ncbi.nlm.nih.gov/pubmed/32038241
http://dx.doi.org/10.3389/fphar.2019.01553