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Platelets induce increased estrogen production through NF-κB and TGF-β1 signaling pathways in endometriotic stromal cells

Endometriosis is estrogen-dependent disorder. Two theories provide the explanations for the increased estrogen production. One is the feed-forward loop model linking inflammation and estrogen production. The more recent model evokes the tissue hypoxia resulting from endometrial debris detached and t...

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Detalles Bibliográficos
Autores principales: Qi, Qiuming, Liu, Xishi, Zhang, Qi, Guo, Sun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987096/
https://www.ncbi.nlm.nih.gov/pubmed/31992765
http://dx.doi.org/10.1038/s41598-020-57997-6