Jedi-1 deficiency increases sensory neuron excitability through a non-cell autonomous mechanism

The dorsal root ganglia (DRG) house the primary afferent neurons responsible for somatosensation, including pain. We previously identified Jedi-1 (PEAR1/MEGF12) as a phagocytic receptor expressed by satellite glia in the DRG involved in clearing apoptotic neurons during development. Here, we further...

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Detalles Bibliográficos
Autores principales: Trevisan, Alexandra J., Bauer, Mary Beth, Brindley, Rebecca L., Currie, Kevin P. M., Carter, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987110/
https://www.ncbi.nlm.nih.gov/pubmed/31992767
http://dx.doi.org/10.1038/s41598-020-57971-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987110/
https://www.ncbi.nlm.nih.gov/pubmed/31992767
http://dx.doi.org/10.1038/s41598-020-57971-2

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