Target protein-oriented isolation of Hes1 dimer inhibitors using protein based methods

Natural products isolation using protein based methods is an attractive for obtaining bioactive compounds. To discover neural stem cell (NSC) differentiation activators, we isolated eight inhibitors of Hes1 dimer formation from Psidium guajava using the Hes1-Hes1 interaction fluorescent plate assay...

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Detalles Bibliográficos
Autores principales: Arai, Midori A., Morita, Kaori, Kawano, Haruka, Makita, Yuna, Hashimoto, Manami, Suganami, Akiko, Tamura, Yutaka, Sadhu, Samir K., Ahmed, Firoj, Ishibashi, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987128/
https://www.ncbi.nlm.nih.gov/pubmed/31992824
http://dx.doi.org/10.1038/s41598-020-58451-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987128/
https://www.ncbi.nlm.nih.gov/pubmed/31992824
http://dx.doi.org/10.1038/s41598-020-58451-3

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