Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

L-type amino acid transporter 1 (LAT1) plays a role in transporting essential amino acids including leucine, which regulates the mTOR signaling pathway. Here, we studied the expression profile and functional role of LAT1 in bladder cancer. Furthermore, the pharmacological activity of JPH203, a speci...

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Detalles Bibliográficos
Autores principales: Maimaiti, Maihulan, Sakamoto, Shinichi, Yamada, Yasutaka, Sugiura, Masahiro, Rii, Junryo, Takeuchi, Nobuyoshi, Imamura, Yusuke, Furihata, Tomomi, Ando, Keisuke, Higuchi, Kosuke, Xu, Minhui, Sazuka, Tomokazu, Nakamura, Kazuyoshi, Kaneda, Atsushi, Kanai, Yoshikatsu, Kyprianou, Natasha, Ikehara, Yuzuru, Anzai, Naohiko, Ichikawa, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987139/
https://www.ncbi.nlm.nih.gov/pubmed/31992742
http://dx.doi.org/10.1038/s41598-020-58136-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987139/
https://www.ncbi.nlm.nih.gov/pubmed/31992742
http://dx.doi.org/10.1038/s41598-020-58136-x

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