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Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma
L-type amino acid transporter 1 (LAT1) plays a role in transporting essential amino acids including leucine, which regulates the mTOR signaling pathway. Here, we studied the expression profile and functional role of LAT1 in bladder cancer. Furthermore, the pharmacological activity of JPH203, a speci...
Autores principales: | Maimaiti, Maihulan, Sakamoto, Shinichi, Yamada, Yasutaka, Sugiura, Masahiro, Rii, Junryo, Takeuchi, Nobuyoshi, Imamura, Yusuke, Furihata, Tomomi, Ando, Keisuke, Higuchi, Kosuke, Xu, Minhui, Sazuka, Tomokazu, Nakamura, Kazuyoshi, Kaneda, Atsushi, Kanai, Yoshikatsu, Kyprianou, Natasha, Ikehara, Yuzuru, Anzai, Naohiko, Ichikawa, Tomohiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987139/ https://www.ncbi.nlm.nih.gov/pubmed/31992742 http://dx.doi.org/10.1038/s41598-020-58136-x |
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