Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells

In this report, we investigated the hepatocytic uptake of rosuvastatin when administered with scutellarin (a Chinese herbal medicine) in rats and the role of organic anion transporting polypeptide 1B1 (OATP1B1) plays in the uptake. Forty-eight rats were randomly divided into two groups according to...

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Detalles Bibliográficos
Autores principales: Liu, Jianming, Guo, Yongmei, Liu, Keqi, Ye, Xiyong, Wang, Fang, Xu, Yanqi, Xia, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987161/
https://www.ncbi.nlm.nih.gov/pubmed/31992796
http://dx.doi.org/10.1038/s41598-020-58303-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987161/
https://www.ncbi.nlm.nih.gov/pubmed/31992796
http://dx.doi.org/10.1038/s41598-020-58303-0

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