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Studying biomolecular folding and binding using temperature-jump mass spectrometry

Characterizing folding and complex formation of biomolecules provides a view into their thermodynamics, kinetics and folding pathways. Deciphering kinetic intermediates is particularly important because they can often be targeted by drugs. The key advantage of native mass spectrometry over conventio...

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Detalles Bibliográficos
Autores principales: Marchand, Adrien, Czar, Martin F., Eggel, Elija N., Kaeslin, Jérôme, Zenobi, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987177/
https://www.ncbi.nlm.nih.gov/pubmed/31992698
http://dx.doi.org/10.1038/s41467-019-14179-x