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Studying biomolecular folding and binding using temperature-jump mass spectrometry
Characterizing folding and complex formation of biomolecules provides a view into their thermodynamics, kinetics and folding pathways. Deciphering kinetic intermediates is particularly important because they can often be targeted by drugs. The key advantage of native mass spectrometry over conventio...
Autores principales: | Marchand, Adrien, Czar, Martin F., Eggel, Elija N., Kaeslin, Jérôme, Zenobi, Renato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987177/ https://www.ncbi.nlm.nih.gov/pubmed/31992698 http://dx.doi.org/10.1038/s41467-019-14179-x |
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