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Estradiol/GPER affects the integrity of mammary duct-like structures in vitro

High estrogen concentration leads to an inflammatory reaction in the mammary gland tissue in vivo; however, the detailed mechanism underlying its specific effects on the breast duct has not been fully clarified. We used 3D-cultured MCF-10A acini as a breast duct model and demonstrated various delete...

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Detalles Bibliográficos
Autores principales: Deng, Yu, Miki, Yoshio, Nakanishi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987193/
https://www.ncbi.nlm.nih.gov/pubmed/31992771
http://dx.doi.org/10.1038/s41598-020-57819-9