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Senolytics: A Translational Bridge Between Cellular Senescence and Organismal Aging

Aging is defined as a progressive decrease in physiological function accompanied by a steady increase in mortality. The antagonistic pleiotropy theory proposes that aging is largely due to the natural selection of genes and pathways that increase fitness and decrease mortality early in life but cont...

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Detalles Bibliográficos
Autores principales: Thoppil, Harikrishnan, Riabowol, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987374/
https://www.ncbi.nlm.nih.gov/pubmed/32039197
http://dx.doi.org/10.3389/fcell.2019.00367