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Structural Insights Into the Transcriptional Regulation of HigBA Toxin–Antitoxin System by Antitoxin HigA in Pseudomonas aeruginosa

HigB-HigA is a bacterial toxin–antitoxin (TA) system in which the antitoxin HigA can mask the endoribonuclease activity of toxin HigB and repress the transcription of the TA operon by binding to its own promoter region. The opportunistic pathogen Pseudomonas aeruginosa HigBA (PaHigBA) is closely ass...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Gao, Zengqiang, Liu, Guangfeng, Geng, Zhi, Dong, Yuhui, Zhang, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987408/
https://www.ncbi.nlm.nih.gov/pubmed/32038588
http://dx.doi.org/10.3389/fmicb.2019.03158