Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway

Cancer cells are characterized by malignant proliferation and aberrant metabolism and are thereby liable to the depletion of nutrients and accumulation of metabolic waste. To maintain cellular homeostasis, cancer cells are prone to upregulating the canonical autophagy pathway. Here, we identified pa...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Gong, Qing, Zhan, Yujuan, Chen, Bonan, Yin, Ting, Lu, Yuhua, Zhang, Yilin, Wang, Huiqi, Ke, Junzi, Du, Biaoyan, Liu, Xiaodong, Xiao, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987457/
https://www.ncbi.nlm.nih.gov/pubmed/32039209
http://dx.doi.org/10.3389/fcell.2019.00397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987457/
https://www.ncbi.nlm.nih.gov/pubmed/32039209
http://dx.doi.org/10.3389/fcell.2019.00397

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