Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens

Trypanosoma brucei evades mammalian immunity by using recombination to switch its surface-expressed variant surface glycoprotein (VSG), while ensuring that only one of many subtelomeric multigene VSG expression sites are transcribed at a time. DNA repair activities have been implicated in the cataly...

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Detalles Bibliográficos
Autores principales: Black, Jennifer Ann, Crouch, Kathryn, Lemgruber, Leandro, Lapsley, Craig, Dickens, Nicholas, Tosi, Luiz R.O., Mottram, Jeremy C., McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988115/
https://www.ncbi.nlm.nih.gov/pubmed/31968257
http://dx.doi.org/10.1016/j.celrep.2019.12.049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988115/
https://www.ncbi.nlm.nih.gov/pubmed/31968257
http://dx.doi.org/10.1016/j.celrep.2019.12.049

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