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Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens
Trypanosoma brucei evades mammalian immunity by using recombination to switch its surface-expressed variant surface glycoprotein (VSG), while ensuring that only one of many subtelomeric multigene VSG expression sites are transcribed at a time. DNA repair activities have been implicated in the cataly...
Autores principales: | Black, Jennifer Ann, Crouch, Kathryn, Lemgruber, Leandro, Lapsley, Craig, Dickens, Nicholas, Tosi, Luiz R.O., Mottram, Jeremy C., McCulloch, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988115/ https://www.ncbi.nlm.nih.gov/pubmed/31968257 http://dx.doi.org/10.1016/j.celrep.2019.12.049 |
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