Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells

How chromosome organization is related to genome function remains poorly understood. Cohesin, loop extrusion, and CCCTC-binding factor (CTCF) have been proposed to create topologically associating domains (TADs) to regulate gene expression. Here, we examine chromosome conformation in embryonic stem...

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Detalles Bibliográficos
Autores principales: Rhodes, James D.P., Feldmann, Angelika, Hernández-Rodríguez, Benjamín, Díaz, Noelia, Brown, Jill M., Fursova, Nadezda A., Blackledge, Neil P., Prathapan, Praveen, Dobrinic, Paula, Huseyin, Miles K., Szczurek, Aleksander, Kruse, Kai, Nasmyth, Kim A., Buckle, Veronica J., Vaquerizas, Juan M., Klose, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988126/
https://www.ncbi.nlm.nih.gov/pubmed/31968256
http://dx.doi.org/10.1016/j.celrep.2019.12.057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988126/
https://www.ncbi.nlm.nih.gov/pubmed/31968256
http://dx.doi.org/10.1016/j.celrep.2019.12.057

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