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Vaccine Against PCSK9 Improved Renal Fibrosis by Regulating Fatty Acid β‐Oxidation

BACKGROUND: Defects in the renal fatty acid β‐oxidation pathway have been implicated in the development of renal fibrosis. Our group has developed a therapeutic vaccine targeting PCSK9 (proprotein convertase subtilisin/kexin type 9), named PCSK9Qβ‐003. In this study, we investigated the potential ef...

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Detalles Bibliográficos
Autores principales: Wu, Danyu, Zhou, Yanzhao, Pan, Yajie, Li, Chang, Wang, Yingxuan, Chen, Fen, Chen, Xiao, Yang, Shijun, Zhou, Zihua, Liao, Yuhua, Qiu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988173/
https://www.ncbi.nlm.nih.gov/pubmed/31870234
http://dx.doi.org/10.1161/JAHA.119.014358