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Identifying critical state of complex diseases by single-sample Kullback–Leibler divergence

BACKGROUND: Developing effective strategies for signaling the pre-disease state of complex diseases, a state with high susceptibility before the disease onset or deterioration, is urgently needed because such state usually followed by a catastrophic transition into a worse stage of disease. However,...

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Detalles Bibliográficos
Autores principales: Zhong, Jiayuan, Liu, Rui, Chen, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988219/
https://www.ncbi.nlm.nih.gov/pubmed/31992202
http://dx.doi.org/10.1186/s12864-020-6490-7