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Identifying critical state of complex diseases by single-sample Kullback–Leibler divergence
BACKGROUND: Developing effective strategies for signaling the pre-disease state of complex diseases, a state with high susceptibility before the disease onset or deterioration, is urgently needed because such state usually followed by a catastrophic transition into a worse stage of disease. However,...
Autores principales: | Zhong, Jiayuan, Liu, Rui, Chen, Pei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988219/ https://www.ncbi.nlm.nih.gov/pubmed/31992202 http://dx.doi.org/10.1186/s12864-020-6490-7 |
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