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A deep learning image-based intrinsic molecular subtype classifier of breast tumors reveals tumor heterogeneity that may affect survival

BACKGROUND: Breast cancer intrinsic molecular subtype (IMS) as classified by the expression-based PAM50 assay is considered a strong prognostic feature, even when controlled for by standard clinicopathological features such as age, grade, and nodal status, yet the molecular testing required to eluci...

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Detalles Bibliográficos
Autores principales: Jaber, Mustafa I., Song, Bing, Taylor, Clive, Vaske, Charles J., Benz, Stephen C., Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Szeto, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988279/
https://www.ncbi.nlm.nih.gov/pubmed/31992350
http://dx.doi.org/10.1186/s13058-020-1248-3