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Fowlerstefin, a cysteine protease inhibitor of Naegleria fowleri, induces inflammatory responses in BV-2 microglial cells in vitro

BACKGROUND: Naegleria fowleri is a free-living amoeba that causes an opportunistic fatal infection known as primary amoebic meningoencephalitis (PAM) in humans. Cysteine proteases produced by the amoeba may play critical roles in the pathogenesis of infection. In this study, a novel cysteine proteas...

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Detalles Bibliográficos
Autores principales: Thái, Thị Lam, Kang, Jung-Mi, Lê, Hương Giang, Lee, Jinyoung, Yoo, Won Gi, Shin, Ho-Joon, Sohn, Woon-Mok, Na, Byoung-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988287/
https://www.ncbi.nlm.nih.gov/pubmed/31996242
http://dx.doi.org/10.1186/s13071-020-3909-6