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Case report: recurrent pituitary adenoma has increased load of somatic variants

BACKGROUND: Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient to explain the causality mechanisms of PA recurrence. CASE...

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Detalles Bibliográficos
Autores principales: Peculis, Raitis, Balcere, Inga, Radovica-Spalvina, Ilze, Konrade, Ilze, Caune, Olivija, Megnis, Kaspars, Rovite, Vita, Stukens, Janis, Nazarovs, Jurijs, Breiksa, Austra, Kiecis, Aigars, Silamikelis, Ivars, Pirags, Valdis, Klovins, Janis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988340/
https://www.ncbi.nlm.nih.gov/pubmed/31996211
http://dx.doi.org/10.1186/s12902-020-0493-x