Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence

Rickettsia are obligate intracellular bacteria that evade antimicrobial autophagy in the host cell cytosol by unknown mechanisms. Other cytosolic pathogens block different steps of autophagy targeting, including the initial step of polyubiquitin coat formation. One mechanism of evasion is to mobiliz...

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Detalles Bibliográficos
Autores principales: Engström, Patrik, Burke, Thomas P., Mitchell, Gabriel, Ingabire, Nadia, Mark, Kevin G., Golovkine, Guillaume, Iavarone, Anthony T., Rape, Michael, Cox, Jeffery S., Welch, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988571/
https://www.ncbi.nlm.nih.gov/pubmed/31611642
http://dx.doi.org/10.1038/s41564-019-0583-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988571/
https://www.ncbi.nlm.nih.gov/pubmed/31611642
http://dx.doi.org/10.1038/s41564-019-0583-6

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