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Revealing the transient conformations of a single flavin adenine dinucleotide using an aerolysin nanopore

Flavin adenine dinucleotide (FAD) as a cofactor is involved in numerous important metabolic pathways where the biological function is intrinsically related to its transient conformations. The confined space of enzymes requires FAD set in its specific intermediate conformation. However, conventional...

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Detalles Bibliográficos
Autores principales: Li, Meng-Yin, Wang, Ya-Qian, Ying, Yi-Lun, Long, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988595/
https://www.ncbi.nlm.nih.gov/pubmed/32110330
http://dx.doi.org/10.1039/c9sc03163d