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HAMA: a multiplexed LC-MS/MS assay for specificity profiling of adenylate-forming enzymes
Adenylation enzymes selecting substrates for ribosomal and nonribosomal protein and peptide biosynthesis have been popular targets of enzyme engineering. Previous standard assays for adenylation specificity have been cumbersome and failed to reflect the competition conditions inside a cell because t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988596/ https://www.ncbi.nlm.nih.gov/pubmed/32110329 http://dx.doi.org/10.1039/c9sc04222a |