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Design, synthesis and application of a new type of bifunctional Le-Phos in highly enantioselective γ-addition reactions of N-centered nucleophiles to allenoates

A novel class of cyclic phosphine derived bifunctional catalysts (Le-Phos) is reported, which can be readily prepared from inexpensive and commercially available starting materials and exhibit good performances in enantioselective γ-addition reactions of N-centered nucleophiles and allenoates under...

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Detalles Bibliográficos
Autores principales: Qiu, Haile, Chen, Xiaofeng, Zhang, Junliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988743/
https://www.ncbi.nlm.nih.gov/pubmed/32055374
http://dx.doi.org/10.1039/c9sc04073k