Development of a DUB-selective fluorogenic substrate

Ubiquitination is a post-translational modification that is involved in a plethora of cellular processes. Target proteins can be specifically modified with a single ubiquitin (Ub) molecule or with complex chains. In recent years, research has focused on deubiquitinating enzymes (DUBs) as potential t...

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Detalles Bibliográficos
Autores principales: Gjonaj, Lorina, Sapmaz, Aysegul, Flierman, Dennis, Janssen, George M. C., van Veelen, Peter A., Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988746/
https://www.ncbi.nlm.nih.gov/pubmed/32110315
http://dx.doi.org/10.1039/c9sc02226k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988746/
https://www.ncbi.nlm.nih.gov/pubmed/32110315
http://dx.doi.org/10.1039/c9sc02226k

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