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Pathological consequences of the unfolded protein response and downstream protein disulphide isomerases in pulmonary viral infection and disease
Protein folding within the endoplasmic reticulum (ER) exists in a delicate balance; perturbations of this balance can overload the folding capacity of the ER and disruptions of ER homoeostasis is implicated in numerous diseases. The unfolded protein response (UPR), a complex adaptive stress response...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988748/ https://www.ncbi.nlm.nih.gov/pubmed/31790139 http://dx.doi.org/10.1093/jb/mvz101 |