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Pathological consequences of the unfolded protein response and downstream protein disulphide isomerases in pulmonary viral infection and disease

Protein folding within the endoplasmic reticulum (ER) exists in a delicate balance; perturbations of this balance can overload the folding capacity of the ER and disruptions of ER homoeostasis is implicated in numerous diseases. The unfolded protein response (UPR), a complex adaptive stress response...

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Detalles Bibliográficos
Autores principales: Chamberlain, Nicolas, Anathy, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988748/
https://www.ncbi.nlm.nih.gov/pubmed/31790139
http://dx.doi.org/10.1093/jb/mvz101