Cargando…

Stereoselective Four-Component Synthesis of Functionalized 2,3-Dihydro-4-Nitropyrroles

We report a metal-free and stereoselective four-component reaction between α-ketoamides, amines, aromatic aldehydes and β-nitroalkenes or β-pivaloxy-nitroalkanes to obtain 2,3-dihydro-4-nitropyrroles functionalized in every position. The heterocycles accessible using this reaction may have utility i...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Dong, Ma, Xinyue, Dong, Linru, Feng, Hairong, Yu, Peng, Désaubry, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988783/
https://www.ncbi.nlm.nih.gov/pubmed/32039135
http://dx.doi.org/10.3389/fchem.2019.00810