Cargando…

Stereoselective Four-Component Synthesis of Functionalized 2,3-Dihydro-4-Nitropyrroles

We report a metal-free and stereoselective four-component reaction between α-ketoamides, amines, aromatic aldehydes and β-nitroalkenes or β-pivaloxy-nitroalkanes to obtain 2,3-dihydro-4-nitropyrroles functionalized in every position. The heterocycles accessible using this reaction may have utility i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Dong, Ma, Xinyue, Dong, Linru, Feng, Hairong, Yu, Peng, Désaubry, Laurent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988783/ https://www.ncbi.nlm.nih.gov/pubmed/32039135 http://dx.doi.org/10.3389/fchem.2019.00810

Ejemplares similares

Synthesis and Anti-Trypanosoma cruzi Biological Evaluation of Novel 2-Nitropyrrole Derivatives
por: Mathias, Fanny, et al.
Publicado: (2022)

Carbohydrates as enantioinduction components in stereoselective catalysis
por: Henderson, Alexander S., et al.
Publicado: (2016)

Highly stereoselective gram scale synthesis of all the four diastereoisomers of Boc-protected 4-methylproline carboxylates
por: Sun, Kehuan, et al.
Publicado: (2019)

Asymmetric synthesis of dihydro-1,3-dioxepines by Rh(ii)/Sm(iii) relay catalytic three-component tandem [4 + 3]-cycloaddition
por: Xu, Chaoran, et al.
Publicado: (2021)

Iridium-promoted deoxyglycoside synthesis: stereoselectivity and mechanistic insight
por: Pal, Kumar Bhaskar, et al.
Publicado: (2020)

Expression of concern: Highly stereoselective gram scale synthesis of all the four diastereoisomers of Boc-protected 4-methylproline carboxylates
por: Sun, Kehuan, et al.
Publicado: (2023)

Stereoselective synthesis of (+)-5-thiosucrose and (+)-5-thioisosucrose
por: Ueda, Atsushi, et al.
Publicado: (2020)

Efficient synthesis of chiral 2,3-dihydro-benzo[b]thiophene 1,1-dioxides via Rh-catalyzed hydrogenation
por: Liu, Gongyi, et al.
Publicado: (2019)

Stereoselective synthesis of four possible isomers of streptopyrrolidine
por: Mohapatra, Debendra K, et al.
Publicado: (2011)

Highly stereoselective and enantiodivergent synthesis of cyclopropylphosphonates with engineered carbene transferases
por: Ren, Xinkun, et al.
Publicado: (2022)

Efficient enzymatic synthesis of chiral 2,3-dihydro-1,4-benzodioxane motif using engineered Candida antarctica lipase B
por: Wu, Zhiyun, et al.
Publicado: (2023)

Stereoselective synthesis and application of isopulegol-based bi- and trifunctional chiral compounds
por: Le, Tam Minh, et al.
Publicado: (2020)

Direct, stereoselective thioglycosylation enabled by an organophotoredox radical strategy
por: Ji, Peng, et al.
Publicado: (2020)

Novel practical stereoselective synthesis of a bicyclic hydantoino-thiolactone as the key intermediate for production of (+)-biotin
por: Shu, Lei, et al.
Publicado: (2023)

Stereoselective total synthesis of parthenolides indicates target selectivity for tubulin carboxypeptidase activity
por: Freund, Robert R. A., et al.
Publicado: (2019)

Stereoselective synthesis of protected l- and d-dideoxysugars and analogues via Prins cyclisations
por: Beattie, Ryan J., et al.
Publicado: (2016)

Highly functionalized pyrrolidine analogues: stereoselective synthesis and caspase-dependent apoptotic activity
por: Kumar, Raju Suresh, et al.
Publicado: (2018)

Stereoselective synthesis of unnatural α-amino acid derivatives through photoredox catalysis
por: Shatskiy, Andrey, et al.
Publicado: (2021)

Eco-friendly reactions in PEG-400: a highly efficient and green approach for stereoselective access to multisubstituted 3,4-dihydro-2(1H)-quinazolines using 2-aminobenzylamines
por: Sharma, Nutan, et al.
Publicado: (2018)

Stereoselective synthesis of macrocyclic peptides via a dual olefin metathesis and ethenolysis approach
por: Mangold, Shane L., et al.
Publicado: (2015)

Stereoselective synthesis of alkyl-, aryl-, vinyl- and alkynyl-substituted Z-enamides and enol ethers
por: Caramenti, Paola, et al.
Publicado: (2019)

Family-level stereoselective synthesis and biological evaluation of pyrrolomorpholine spiroketal natural product antioxidants
por: Verano, Alyssa L., et al.
Publicado: (2017)

Ritter-type iodo(iii)amidation of unactivated alkynes for the stereoselective synthesis of multisubstituted enamides
por: Chai, Jinkui, et al.
Publicado: (2021)

Stereoselective synthesis of C3-tetrasubstituted oxindoles via copper catalyzed asymmetric propargylation
por: Wang, Jiao-Mei, et al.
Publicado: (2022)

Microwave-Assisted Synthesis of Novel 2,3-Dihydro-4-Pyridinones
por: Saeed, Bahjat A., et al.
Publicado: (2010)

Stereoselective Synthesis of Biologically Relevant Tetrahydropyridines and Dihydro-2H-pyrans via Ring-Expansion of Monocyclopropanated Heterocycles
por: Eckl, Robert, et al.
Publicado: (2021)

Highly efficient synthesis and stereoselective migration reactions of chiral five-membered aza-spiroindolenines: scope and mechanistic understanding
por: Wu, Qing-Feng, et al.
Publicado: (2016)

Stereoselective cobalt-catalyzed halofluoroalkylation of alkynes
por: Wu, Guojiao, et al.
Publicado: (2018)

Regio- and stereoselective intermolecular carbolithiation reactions
por: Marsico, G., et al.
Publicado: (2020)

Stereoselective degradation behaviour of carfentrazone-ethyl and its metabolite carfentrazone in soils
por: Duan, Jinsheng, et al.
Publicado: (2018)

Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction
por: Ni, Qijian, et al.
Publicado: (2015)

The Stereoselective Nitro-Mannich Reaction in the Synthesis of Active Pharmaceutical Ingredients and Other Biologically Active Compounds
por: Faisca Phillips, Ana Maria, et al.
Publicado: (2020)

Ru-catalyzed isomerization of ω-alkenylboronates towards stereoselective synthesis of vinylboronates with subsequent in situ functionalization
por: Ho, Guo-Ming, et al.
Publicado: (2020)

Stereoselective synthesis of [2.2]triphenylenophanes via intramolecular double [2 + 2 + 2] cycloadditions
por: Kawai, Yuya, et al.
Publicado: (2023)

Efficient and stereoselective synthesis of sugar fused pyrano[3,2-c]pyranones as anticancer agents
por: Kumar, Sandeep, et al.
Publicado: (2023)

Efficient and stereoselective one-pot synthesis of benzo[b]oxazolo[3,4-d][1,4]oxazin-1-ones
por: Zhao, Hongyi, et al.
Publicado: (2020)

Three-Component Stereoselective Enzymatic Synthesis of Amino-Diols and Amino-Polyols
por: Ford, Grayson J., et al.
Publicado: (2022)

Effect of hydroxyl on antioxidant properties of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one to scavenge free radicals
por: Chen, Zhifei, et al.
Publicado: (2021)

Orthorhombic polymorph of (2E)-2-(2,3-dihydro-1H-inden-1-ylidene)-2,3-dihydro-1H-inden-1-one
por: Li, Hairong, et al.
Publicado: (2012)

Catalytic asymmetric synthesis of N-substituted tetrahydroquinoxalines via regioselective Heyns rearrangement and stereoselective transfer hydrogenation in one pot
por: Huang, Jin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kkdtt2uihik2411ta7h60frmdh